2025's Best Menopause Supplements – What Actually Works for Hot Flashes & Hormone Balance?
Menopause brings a wave of changes to the body: hot flashes, energy shifts, brain fog, mood swings, and metabolism slowdowns, just to name a few. And while there are plenty of supplements claiming to ease the transition, not all are created equal. Many are packed with fillers, lack key nutrients for hormone balance, or simply don't deliver results for menopause symptoms.
That's why finding a high-quality menopause supplement for hot flash relief and hormone balance is so important. But let's be honest: sifting through endless ads, celebrity endorsements, and too-good-to-be-true claims can feel overwhelming. Some brands push flashy marketing over real science, making it difficult to know what actually works for menopause symptoms.
That's exactly why we created this guide. We've done the research and found menopause supplements that are backed by science, trusted by real women, and designed to support hormonal balance, energy, and overall well-being during menopause. Because menopause isn't just something to "get through"… It's a new phase of life, and the right support can make all the difference.
Here are our TOP 5 menopause supplements for 2025!
Dr. Kellyann & ME Peri + Menopause
Meno Menopause Vitamin Capsules
Just Ingredients Menopause+
Bonafide Relizen
Estroven Menopause Relief + Energy
Alloy M4
One A Day Menopause Formula
Olly Mellow Menopause
Winona HRT Menopause Treatments
Centrum Menopause Support
Menopause brings a wave of changes to the body: energy shifts, brain fog, and metabolism slowdowns, just to name a few. And while there are plenty of supplements claiming to ease the transition, not all are created equal. Many are packed with fillers, lack key nutrients, or simply don't deliver results. But which one does it best? Well, that's the million-dollar question I'm trying to find the answer to.
👉 Click here to skip ahead to my top choice!
Putting Menopause Supplements to the Test
As a registered dietitian with over 10 years of experience, I know that not all menopause supplements are created equal. Some come in pill form, some as gummies, and others as drinkable powders. I wanted to find the best ones based on effectiveness for hot flashes and hormone balance, ingredient quality, and whether they're actually worth your money.
Here's how I narrowed it down:
- I focused only on menopause-support supplements—no general multivitamins or unrelated wellness products.
- I ruled out supplements with just one or two ingredients. A well-rounded formula is key to comprehensive menopause support.
- I researched ingredient lists, certifications, and health claims to ensure the products were backed by science, not just marketing.
Then came the real test:
I took each supplement consistently for eight weeks to measure its effects on menopause symptoms.- I tracked changes in hot flashes, mood, energy levels, and overall satisfaction.
- I noted any side effects or benefits beyond just menopause symptoms.
- I rated them based on effectiveness, ingredient quality, ease of use, and overall experience.
The Factors That Mattered Most for a Menopause Supplement
- Ingredients: High-quality, research-backed ingredients that actually support hormonal health and hot flash relief.
- Effectiveness: Noticeable improvements in hot flashes, mood, and energy levels.
- Ease of Use: Simple and convenient enough for daily use.
- Clean Formula: No artificial fillers, preservatives, or questionable additives.
- Absorption: A format that allows for maximum nutrient uptake (no wasted ingredients).
- Price: Good value for the quality and results provided.
My Non-Negotiables
When it comes to what I put in my body, quality is key. The best menopause supplements must contain science-backed ingredients from trusted sources. No unnecessary fillers, no artificial junk. And if it's hard to take or doesn't fit into my routine, I won't use it consistently. The best supplement is the one you'll actually take daily.
So, What's the Best Menopause Supplement?
After weeks of testing and research, I found my top pick: one that actually made a difference in how I felt during menopause. Keep reading for the full breakdown of each supplement I tested and why Mixhers Menopause stood out as the best on the market!
Mixhers Menopause
What I Love:
- Reduces hot flashes and balances hormones naturally
- Boosts mood, improves energy levels, and supports overall vitality during menopause
- Includes a potent blend of phytoestrogens like kwao krua root, black cohosh, and maca root
- Essential vitamins such as Vitamin B6, B12, and Biotin to enhance health and well-being
- All-natural, non-GMO, and 100% vegan-friendly
- Gluten-free and nut-free
- Supports libido and healthy hormonal function
What Could Be Better:
Limited flavor options
Why I Love Mixhers Menopause:
Clinically Backed Ingredients
Thoughtfully formulated with powerful, research-backed ingredients that support hormonal balance, energy, and overall well-being during menopause.
Easy & Delicious
A simple, tasty drink mix that fits seamlessly into your daily routine… because taking care of your hormonal health shouldn't feel like a chore.
Feel-Good Formula
No artificial junk, just clean, high-quality ingredients designed to help you feel your best during menopause.
Menopause is a transformative stage, but the challenges that come with it (like hot flashes, mood swings, and fatigue) don't have to be your new normal. Mixhers Menopause was formulated to help women manage the symptoms of menopause with natural, scientifically-backed ingredients.
The powerful trio of phytoestrogens—kwao krua root, black cohosh, and maca root—work together to restore hormonal balance and provide relief from common symptoms. Unlike synthetic alternatives, this liquid formula ensures fast and effective absorption.
If you're looking for a natural, effective way to navigate menopause, Mixhers Menopause is the best option out there. It doesn't just mask symptoms—it nourishes your body and supports long-term hormonal wellness.
What You Can Expect:
- Reduced Hot Flashes: Natural phytoestrogens help balance hormones and reduce the frequency and intensity of hot flashes.
- Improved Mood & Energy: Essential vitamins support mood regulation and help maintain energy levels throughout the day.
- Better Sleep & Overall Well-being: When your hormones are balanced, you feel more like yourself again.
Runner Up:
Dr. Kellyann & ME Peri + Menopause
What I Love:
- Formulated by a doctor with menopause expertise
- Contains clinically studied ingredients for hormone support
- Includes adaptogens and botanical extracts
What Could Be Better:
- Capsules aren't as convenient as liquid formulas
- Requires multiple capsules per day
- May take longer to see noticeable effects
- Higher price point compared to other options
Final Thoughts:
While the doctor-formulated approach and quality ingredients are impressive, the capsule format and slower absorption make it less convenient than liquid alternatives like Mixhers Menopause.
Other Contenders We Tested
Meno Menopause Vitamin Capsules
What I Love:
- Comprehensive vitamin and mineral blend
- Includes black cohosh and red clover
- Targets multiple menopause symptoms
What Could Be Better:
- Large capsule size may be difficult to swallow
- Takes several weeks to see full benefits
- Multiple capsules required daily
Final Thoughts:
A solid all-in-one approach to menopause support with traditional botanicals, though patience is required for results.
Just Ingredients Menopause+
What I Love:
- Clean, transparent ingredient sourcing
- No artificial fillers or additives
- Third-party tested for purity
What Could Be Better:
- Limited ingredient variety compared to others
- Premium pricing for simpler formula
- May not address all menopause symptoms comprehensively
Final Thoughts:
Perfect for those prioritizing clean ingredients, though the minimalist approach may not address all symptoms comprehensively.
Bonafide Relizen
What I Love:
- Non-hormonal pollen extract formula
- Clinically studied for hot flashes
- No soy or phytoestrogens
What Could Be Better:
- Only targets hot flashes, not other symptoms
- May cause mild allergic reactions in sensitive individuals
- Expensive for a single-ingredient supplement
Final Thoughts:
An innovative, targeted solution for hot flashes with unique pollen extract, but limited scope for comprehensive menopause support.
Estroven Menopause Relief + Energy
What I Love:
- Includes energy-boosting B vitamins
- Contains black cohosh and soy isoflavones
- Widely available in stores
What Could Be Better:
- Contains soy which some prefer to avoid
- May cause digestive upset in sensitive users
- Capsule form may be less convenient than liquid
Final Thoughts:
A mainstream option that addresses fatigue alongside menopause symptoms, though soy content may not suit everyone.
Alloy M4
What I Love:
- Personalized approach with telemedicine support
- Combines supplements with lifestyle guidance
- Modern, science-based formulation
What Could Be Better:
- Requires ongoing subscription commitment
- Higher cost due to telemedicine component
- May not be suitable for those preferring standalone supplements
Final Thoughts:
An innovative approach combining supplements with professional guidance, ideal for those wanting comprehensive support but requiring budget consideration.
Olly Mellow Menopause
What I Love:
- Pleasant gummy format
- Includes ashwagandha for stress support
- Affordable and accessible
What Could Be Better:
- Contains added sugars and flavors
- Gummy format may be less potent than capsules
- Multiple gummies required daily
Final Thoughts:
A tasty, stress-focused option that's easy to take, though the gummy format may compromise ingredient potency.
One A Day Menopause Formula
What I Love:
- Simple once-daily dosing
- Trusted brand with wide availability
- Budget-friendly option
What Could Be Better:
- Basic formula with limited ingredients
- May not address severe symptoms effectively
- Generic approach without specialized benefits
Final Thoughts:
A convenient, no-frills option from a trusted brand, but may fall short for those with more complex menopause needs.
Winona HRT Menopause Treatments
What I Love:
- Prescription hormone replacement therapy
- Telehealth platform for easy access
- Personalized treatment plans
What Could Be Better:
- Requires prescription and medical consultation
- Potential side effects and contraindications
- Not suitable for all women due to health restrictions
Final Thoughts:
A medical-grade solution for those needing hormone replacement, but requires careful medical supervision and may not be suitable for everyone.
Centrum Menopause Support
What I Love:
- Established brand with quality standards
- Includes essential vitamins and minerals
- Widely available and affordable
What Could Be Better:
- Generic formula not specifically optimized
- Lower potency compared to specialized brands
- May not provide comprehensive symptom relief
Final Thoughts:
A reliable, basic option for general menopause support, but may lack the specialized approach of more targeted formulations.
Why Mixhers Menopause is the Clear Winner
When it comes to navigating the challenges of menopause, Mixhers Menopause stands out as the ultimate game-changer. With a carefully crafted formula that combines potent, naturally sourced ingredients like black cohosh, ashwagandha, and vitamin E, it's designed not only to alleviate the most common symptoms like hot flashes and mood swings but also to support overall wellness.
And unlike many competitors, Mixhers doesn't rely on synthetic hormones or fillers, making it the perfect choice for women who want a clean, effective solution. Plus, the brand's commitment to quality, customer satisfaction, and ingredient transparency ensures that you're getting the best for your body without compromise. If you're ready to reclaim your balance and live your best life during menopause, Mixhers Menopause is the clear choice.
